Stockchase Opinions

Paul MacDonaldAstrazeneca P L CAZNPAST TOP PICKMar 21, 2018

(A Top Pick May 10/17, Up 16%) It's a diversified biopharma out of the UK. Surprised many by annoucning phase 2 drug trial in lung cancer--a frontrunner in this space. Their main drivers is their immunotherapy business. A great growth profile in the industry, but need to execute on a few of these trials in the next 6-12 months. Own it with BMY-N and MRK-N and not alone.

$34.61

Stock price when the opinion was issued

$185.65

As of May 27, 2026. Market Open.

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(A Top Pick May 16/25, Up 31%)

Very advanced pipeline will add significant revenue. Good story still intact.

HOLD

The chart has a gentle uptrend since 2022, and had a breakout the past year. It could pullback slightly to $85, the 2024 high. As long as it doesn't fall below that, he'd probably hold it.

BUY

Likes it. Their cancer drug franchise turned out to be a lot stronger than he expected. Has a better portfolio than Abbvie.

PAST TOP PICK
(A Top Pick Nov 01/24, Up 31%)

Are best in class innovators in pharma drugs. A good performer in the past year. They aim $80 billion revenue by 2030 or 7% annual growth. Their drug pipeline looks positive, given good trial data. Still likes it.

BUY

Has broad platform of diseases they treat. Trades around 15x PE and pays a 2% dividend yield. Shares are still snapping back from some news in China last year, so there's more room to recover.

BUY

Abbvie and AZN are two good healthcare stocks, a sector in which you must be picky because of weakness. Both trade around 15x and pay around a 3% dividend yield.

BUY

In oncology, but he isn't deeply familiar with its product pipeline. He can say, with quite a bit of confidence, that they've been improving on fundamentals since around 2017-18. ROC marched up from 6% to 13%, very consistent. Pretty good valuation at 13x EV/EBITDA. Well run.

He doesn't get too hung up on a weak couple of years. If the fundamentals are there, you just have to wait it out.

TOP PICK

Likes the pipeline. A number of candidates to seek approval in the next couple of years, which will be a catalyst for earnings going forward. Fairly productive R&D engine. Also growth through tuck-in acquisitions. Relatively attractively priced given current growth outlook. Going to be second-fastest growing drug stock in Europe behind NVO. Yield is 3.06%.

(Analysts’ price target is $85.38)
PAST TOP PICK
(A Top Pick Apr 19/24, Up 2%)

Chart did fine for a while, but then employees in China were under investigation. Results on one drug were interpreted very negatively. Phase 3 trials this year provide a lot of potential catalysts. Great suite of offerings. Not expensive.

PAST TOP PICK
(A Top Pick Mar 19/24, Up 5%)

Big breakthroughs in cancer. One drug failed recently. We're in the midst of a malaise of selling and going to cash. Great story.

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Curated by Michael O'Reilly since 2020.
1550+ opinions with 4.81 rating (one of the best performing expert).

PAST TOP PICK
(A Top Pick Feb 06/25, Down 1.9%)Stockchase Research Editor: Michael O'Reilly

Our PAST TOP PICK with AZN has triggered its stop at $71.  To remain disciplined, we recommend covering the position at this time.  This will result in a net investment gain of 1%, when combined with our previous guidance.    

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PAST TOP PICK
(A Top Pick Feb 06/25, Up 9.6%)Stockchase Research Editor: Michael O’Reilly

Our PAST TOP PICK with AZN is progressing well.  To remain disciplined, we recommend trailing up the stop (from $64) to $71 at this time.

PAST TOP PICK
(A Top Pick Feb 16/24, Up 23%)

They rallied last summer, then faced headwinds last fall when a cancer drug failed to perform in trials and there was an investigation in their large Chinese business. Both problems are clearing now. They have a drug pipeline that should become a great growth story. Trades at 15x PE. 

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Curated by Michael O'Reilly since 2020.
1550+ opinions with 4.81 rating (one of the best performing expert).

TOP PICK
Stockchase Research Editor: Michael O'Reilly

We reiterate AZN as a TOP PICK.  Recently reported earnings indicated a 19% increase in earnings and revenues.  Management announced positive development on 9 new drugs worth $5 billion in future revenues and a plan to invest over $800 million in Ontario creating 700 jobs.  The shares trade at 18x earnings and support a 30% ROE.  We recommend trailing up the stop (from $52) to $64, looking to achieve $88 -- upside potential of 21%.  Yield 1.4%

(Analysts’ price target is $88.24)
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Curated by Michael O'Reilly since 2020.
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TOP PICK
Stockchase Research Editor: Michael O'Reilly

The big pharma is developing a GLP-1 weight loss treatment that avoids injections -- a big game changer - and trials are looking good.  The stock trades at 32x earnings and supports a 16% ROE.  We recommend setting a stop-loss at $52, looking to achieve $88 -- upside potential of 30%.  Yield 2.2%

(Analysts’ price target is $88.01)