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John Sinkins, CFA Aptose Biosciences APS-T BUY May 14, 2003

Received patent approval on one of their processes. New drugs for cancer are being tested in Mexico and USA. You have to keep an eye on this one.

John Sinkins, CFA

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$1.410

Stock price when the opinion was issued

biotechnology pharmaceutical

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BUY

Getting a lot of patent approvals. A growth story in the making. Have an extensive profile. Have recently flushed out their balance sheets with an issue. A very interesting story, but can be somewhat volatile.

BUY

A very interesting stock at this price. Good cancer drugs. Still awaiting trial completions in the US. Also have new products.

DON'T BUY

Highly speculative. A very high number of shares outstanding. Trading below its 50/200 day moving average. Struggling to hold on to its current level. Have had 10 quarters of losses.

WEAK BUY

Not their favorite biotech. Cancer Institute has given them a lot of money for phase two studies. Possibly have a very elegant solution. Expect there will be a lot of news as phase two trials proceed. Volatile. Early stages so only buy a little.

DON'T BUY

Have done well getting approvals on their products but the stock hasn't done very much. Would like to get rid of his holdings, but not at this price.

BUY

One of the more undervalued of the biotech's. Have a number of interesting products that are being developed. Has been disappointed in the stock performance. Need some news that will push the valuation.

BUY

A very interesting company. Has always been a bit of a disappointment. Once they get their FDA approval then the stock should go.

SELL

At this point, it's a lottery ticket, so for a conservative, fundamental investor, he would call it a sell. Their therapy for pancreatic cancer hasn't been shown to be effective. Be very, very cautious over the next couple of months because it's an orphan stock and you are going into tax loss selling.

RISKY

An old story, but re-invigorated by an impressive management team. Speculative. Recent sell off in biotech has not helped them.

PARTIAL BUY

Don't get scared of parabolic moves. The chart looks very good. It has shot up in the last 6 weeks. Its next move could be just under $6 pretty quickly. Relative strength vs. the S&P looks very good. However, expect volatility. Own a small holding.

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John Sinkins, CFA Aptose Biosciences APS-T BUY May 14, 2003

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